Sunday, June 15, 2025

Questions and Solutions About Migraine Therapies

Migraine assaults aren’t simply head ache. They’re a part of migraine illness, a neurologic dysfunction, they usually contain all kinds of signs that may embrace intense headache assaults, notably occurring on one aspect of the pinnacle; sensitivity to mild, sounds and smells; tingling or numbness in your arms and/or legs, temper modifications and intense fatigue, amongst different signs.

This persistent situation may be tough to deal with, however there are a variety of completely different migraine remedies on the market. We reached out to Jessica Ailani, M.D., FAHS,, neurologist and director of Georgetown Headache Middle, to search out out extra about remedy choices for folks dwelling with migraine illness.

What sorts of remedies can I exploit for the onset of signs from a migraine assault? (non-prescription, prescription)

Remedy used originally of migraine signs are referred to as acute remedies. These vary from over-the counter drugs and coverings corresponding to NSAIDs (nonsteroidal anti-inflammatory medication) like aspirin, ibuprofen and naproxen to acetaminophen, and mixture remedies like aspirin/acetaminophen/caffeine to gadgets and prescription drugs.

Some folks discover ice packs and chilly rubs to be useful throughout an assault as nicely. Although there will not be many research that assist this, it’s common for folks with migraine illness to make use of ice on their head and neck throughout an assault.

If over-the-counter remedies will not be efficient, it’s time to talk to your healthcare supplier (HCP) about prescription drugs.

Neuromodulation gadgets are a non-medication solution to deal with a migraine assault after it begins however should still require a prescription. Units work in numerous methods to scale back the irregular signaling within the mind concerned throughout a migraine assault. FDA-cleared gadgets for acute remedy of migraine prevention embrace sTNS (Cefaly), distant electrical neuromodulation (Nerivio), sTMS (e-Neura), eCOTs (Relivion) and nVNS (gammaCore).

The most typical prescription remedy prescribed for migraine is a category often called triptans. These are drugs you utilize as wanted for an assault that work on blocking chemical compounds which can be launched in the course of the ache part of a migraine assault. Triptans may be tablets you swallow, tablets that dissolve in your mouth or nasal sprays, and one comes as a self-injection.

The completely different types are vital as a result of migraine may cause nausea and vomiting. If nausea or feeling like you may’t eat or drink throughout an assault is widespread for you, utilizing a medicine by nostril or by injection is vital. Triptans shouldn’t be used greater than 10 days a month or they will trigger one thing often called rebound headache or remedy overuse complications (MOH). Additionally they don’t work nicely late in a migraine assault.

One other class of acute remedy are gepants. Gepants are additionally used particularly for migraine assaults and may be taken as a pill, an oral dissolvable pill or a nasal spray. They’ve fewer uncomfortable side effects than triptans and can be utilized in a wider vary of populations, however they is probably not as efficient as triptans for some folks. Gepants block a protein referred to as CGRP that’s concerned in what can convey on a migraine assault. One gepant has been proven to work if taken in the course of the prodrome part or aura (earlier than the ache of migraine begins). Gepants will not be thought to trigger rebound headache and may be useful for these with extra frequent assaults.

A 3rd class of acute remedy are ergots. Ergots block a wider variety of chemical compounds concerned in migraine, to allow them to generally be efficient when different remedies will not be. Ergots may be taken as a nasal spray or injection and may work early or later in a migraine assault.

Are there remedies accessible to stop migraines? (non-prescription, prescription)

To scale back the frequency of migraine assaults and enhance incapacity, preventive remedy is used. Preventive remedy consists of behavioral therapies, vitamin dietary supplements, neuromodulation gadgets and drugs that may be prescribed by your clinician.

For all folks with migraine, way of life modifications must be thought-about. These embrace:

  • Common sleep and wake schedules
  • Common consuming instances
  • Good hydration with water — drink water if you find yourself thirsty
  • Common train — transfer your physique day by day even should you’re having a headache assault. Strive stretching in place or holding a delicate yoga pose.
  • Regulate stress — meditate, observe deep respiration, get common train and motion, journal, take heed to calming music, step away from damaging conditions

Behavioral interventions can be utilized alone or along with remedy to assist cut back migraine frequency. One of the best studied behavioral strategies to scale back frequent migraine assaults embrace biofeedback, progressive muscle rest and cognitive behavioral remedy should you’re experiencing generalized anxiousness or anxiousness about your migraine assaults or struggling to deal with persistent ache.There are different sorts of intervention which can be being studied, together with mindfulness and acceptance and dedication remedy.

Vitamin dietary supplements which have good proof for migraine prevention embrace riboflavin, magnesium and butterbur. Butterbur must be used underneath the instruction of an HCP as a result of utilizing the fallacious kind could also be harmful on your liver well being. There are different dietary supplements used for migraine prevention, however the research will not be as robust that they’re efficient.

Many drugs can be found to stop migraine. There are migraine-specific remedies that block CGRP, which is a protein concerned in inflicting migraine. Tablets that block CGRP may be given each day or each different day. Injections of monoclonal antibodies that block CGRP may be given month-to-month or each three months. Tablets may be simpler for some folks to take, however a month-to-month or quarterly injection could also be extra handy. To decide about what remedy could also be finest for you, it’s a good suggestion to have a dialog together with your HCP and assessment potential uncomfortable side effects.

Learn: How Shared Resolution-Making Can Result in Higher Healthcare >>

There are additionally drugs which can be older and cheap as a result of they’ve been round for many years which have been discovered to be efficient in decreasing migraine frequency. These embrace some blood strain drugs, some anti-seizure drugs and some particular antidepressants.

For folks with persistent migraine (greater than 15 migraine days per thirty days for 3 months, the place eight headache days have migraine traits), injections with onabotulinumtoxin A (Botox) is an FDA-approved remedy possibility as nicely. A skilled injector follows a selected injection protocol to offer the remedy each 12 weeks to scale back migraine frequency and incapacity.

Lastly, there are the neuromodulation gadgets talked about above.

When ought to I think about using preventive remedy?

In case you have six or extra migraine assaults per thirty days, you must think about beginning preventive remedy.

You must also focus on preventive remedy together with your HCP you probably have two or extra migraine assaults per thirty days and also you’re lacking work or life occasions, you don’t have a superb acute remedy that works for assaults, or you’ve gotten assaults related to extreme signs (corresponding to muscle weak point in the course of the migraine assault).

How can I decide what remedy will work nicely for me?

Right now, there isn’t a nice solution to know what remedy will be just right for you with out attempting completely different choices and seeing what works.

Are there any different therapies, corresponding to cognitive behavioral remedy (CBT), acupuncture, or biofeedback, that I ought to think about?

There’s a physique of proof that biofeedback reduces the variety of migraine assaults folks expertise and the way dangerous their migraine assaults are in comparison with people who find themselves not taking remedy, however the proof doesn’t present that it helps greater than remedy or CBT, which additionally has sturdy proof supporting its effectiveness. Acupuncture has combined proof, however I do advocate that sufferers who’re (and may afford the associated fee and the time without work work) give it a strive as a result of it could possibly assist cut back assault frequency.

Ought to I am going to a headache specialist? How can I discover one?

An excellent place to begin remedy is together with your main care supplier or a normal neurologist, as there are only a few headache specialists within the U.S. In the event you really feel you aren’t bettering or have a number of sorts of headache problems or circumstances that go together with your headache assaults, then a headache specialist could be the subsequent step.

To discover a headache specialist licensed in headache medication, you may search the United Council of Neurological Subspecialty listing.

This academic useful resource was created with assist from Pfizer.

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